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The incremental increase in integrated C-peptide concentrations during the first 30 minutes of hyperglycemia followed the same pattern (9.7 2.0 nmol/L versus 14.1 1.5 nmol/L per 30 minutes, P = 0.01 [Figure 3E]) in people without diabetes

Research demonstrates that meal composition and the order of macronutrient consumption significantly influence L-cell activation patterns

The polymers used in their preparation can be natural, such as gelatin, chitosan, silk fibroin, zein, and collagen, or synthetic, such as poly(-caprolactone), polyglycolide, and polylactic acid [166, 167]